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A muscle cramp charley horse is a sudden, brief, involuntary, painful contraction of a muscle or group of muscles. Cramps commonly occur in healthy people usually middle-aged and elderly people , sometimes during rest, but particularly during or after exercise or at night including during sleep. Leg cramps at night usually occur in the calf and cause plantar flexion of the foot and toes. Dystonias can cause muscle spasm, but symptoms are usually more sustained and recurrent and involve muscles other than those affected by typical leg cramps eg, neck, hand, face, muscles throughout the body. Tetany can cause muscle spasm, but spasm is usually more sustained often with repetitive brief muscle twitches ; it is usually bilateral and diffuse, but isolated carpopedal spasm may occur.
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Tobacco smoking

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What is Bladder Cancer? - Urology Care Foundation

Tobacco smoking is the practice of smoking tobacco and inhaling tobacco smoke consisting of particle and gaseous phases. A more broad definition may include simply taking tobacco smoke into the mouth, and then releasing it, as is done by some with tobacco pipes and cigars. The practice encountered criticism from its first import into the Western world onwards but embedded itself in certain strata of a number of societies before becoming widespread upon the introduction of automated cigarette -rolling apparatus. German scientists identified a link between smoking and lung cancer in the late s, leading to the first anti-smoking campaign in modern history, albeit one truncated by the collapse of Nazi Germany at the end of World War II. Rates of consumption since in the developed world have either peaked or declined. Smoking is the most common method of consuming tobacco, and tobacco is the most common substance smoked.
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What is Bladder Cancer?

Some falsely believe that cigarettes increase energy levels, while also inducing a sense of calm and well-being. However, these assumptions are myths, as smoking actually increases your chances of suffering from chronic fatigue and increased stress over time. This is the result of nicotine, a stimulant found naturally in tobacco products. Nicotine enters the bloodstream quickly and affects brain chemicals, causing a boost in energy levels and a reduction in stress. While this sounds like a positive in favor of smoking, the effects of nicotine are short-lived.
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Nicotine black triangle towards center left tricks the nerve cell neuron into sending a message to release more dopamine yellow dots. Those molecules enter the space synapse between one nerve cell and the next. When they get picked up by neighboring cells, this gives users a feel-good high.
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