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Tanning and Increased Nevus Development in Very-Light-Skinned Children Without Red Hair
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To examine the relationship between tanning and nevus development in very-light-skinned children. Prospective cohort nested within a randomized controlled trial. Skin examinations in 3 consecutive years , , and included full-body counts of nevi, skin color and tanning measurement using colorimetry, and hair and eye color evaluation by comparison with charts. Telephone interviews of parents provided sun exposure, sun protection, and sunburn history. Large managed-care organization and private pediatric offices in the Denver, Colorado, metropolitan area.
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Red hair or ginger hair occurs naturally in one to two percent of the human population , appearing with greater frequency two to six percent among people of Northern or Northwestern European ancestry and lesser frequency in other populations. It is most common in individuals homozygous for a recessive allele on chromosome 16 that produces an altered version of the MC1R protein. Red hair varies in hue from a deep burgundy or bright copper , or auburn , to burnt orange or red-orange to strawberry blond. Characterized by high levels of the reddish pigment pheomelanin and relatively low levels of the dark pigment eumelanin , it is associated with fair skin color , lighter eye color , freckles , and sensitivity to ultraviolet light.