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Full Length Research Paper. Search for this author on: Google Scholar. The aim of the present investigation was to evaluate the impact of Blighia sapida aril level in diet on the growth of albino Wistar rats and their welfare. A quantity of B.
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The nucleotide sequence of Tri4 was determined and the locations of three introns were identified. Analysis of Tri4 mRNA levels revealed that transcription reached maximum levels coincidently with the onset of trichothecene biosynthesis, and then declined fold over the next 8 h. Disruption of Tri4 resulted in the loss of production of both trichothecenes and apotrichodiol and the accumulation of the unoxygenated pathway intermediate trichodiene. These data suggest that the enzyme encoded by Tri4 catalyzes the first oxygenation step in the trichothecene pathway and participates in apotrichodiol biosynthesis.
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